The song "Depression" by American Nightmare is about struggling with feelings of loneliness, isolation, and despair. The lyrics express the intense emotional pain caused by depression, and the overwhelming sense of hopelessness that comes with it. The singer feels like they have no one to turn to and no way to escape the grips of depression. They express a deep sense of frustration and anger, feeling like there is no relief in sight. The lyrics convey a sense of desperation and a plea for help, as the singer feels like they are being consumed by their depression. Overall, the song captures the raw and intense emotions that come with battling depression, and the overwhelming sense of desperation that can come with it.