The song "Eyes Wide" by Handsome Ghost is about two people who have lost their sense of adventure and spontaneity in life. They used to be fearless and brave, but now they feel restless and trapped in a monotonous routine. However, the narrator suggests that they could shake things up and rediscover the thrill of life by taking a spontaneous road trip and leaving their regrets behind. The chorus is about the desire to feel truly alive again and to experience the world with open eyes and an open heart. The song's overall message seems to be that it's never too late to take a risk and try something new. The narrator is urging the listener to let go of fear and embrace the unknown, because that's where the magic happens. By facing the uncertainty of life with eyes wide open, we can rediscover the joy and wonder that we may have lost along the way.