The song "Isaiah 53:1-6 (Profession)" by Hillsong Worship is a reflection on the prophecy in the book of Isaiah about the coming of the Messiah. The song begins with a question about the reception of the message about the coming of the Messiah, asking who has believed what they have heard. The song then describes the humble appearance and rejection of the Messiah, who grew up like a young plant and had no desirable physical qualities. Despite this, he was despised and rejected by people, familiar with sorrow and grief. The song then proclaims that this despised and rejected figure is the one who carried the grief and sorrows of humanity, though people regarded him as punished by God. The following lines describe how the Messiah was pierced for humanity's transgressions and suffered so that we may have peace and healing. The song concludes by acknowledging the sinfulness of humanity and how we all have gone astray, but that the Lord has laid upon the Messiah the iniquity of us all. In summary, the song is a reflection upon the prophecy of Isaiah, which foretells the coming of a humble and suffering Messiah who will bear the sins of humanity.