The song "One Good Reason" by Justin Jesso is about a relationship that has lost its spark and passion. The couple used to be close and intimate, but now they sleep on separate sides of the bed and lead different lives. Despite this, they still call it love, but there is a lack of communication and clarity in their relationship. Jesso expresses the frustration of not knowing where he stands with his partner and begs for one good reason to either stay or walk away. He has lost his religion and faith in their relationship and wants his partner to be upfront and honest about their feelings. The repetition of "Give me one good reason" emphasizes his desperation for an explanation and a resolution. Overall, "One Good Reason" is a heartfelt plea for clarity and honesty in a struggling relationship. It highlights the importance of communication and the pain of uncertainty.