"Departure" by Jay Electronica is a deeply personal and introspective song that explores themes of loss, struggle, and the need for change. The lyrics depict the narrator's emotional turmoil, as they witness the harsh realities of their neighborhood and experience the pain of losing a friend, Minnie, to violence. The narrator's desperation is evident as they call out to God for help but receive no response. The song also touches upon the narrator's desire to escape their current situation and pursue a career in rap. They feel trapped and suffocated by the negative circumstances surrounding them, such as their cousin Mookie's involvement with drugs. The decision to leave home and move to Manhattan is seen as a way to start afresh and pursue their dreams. Throughout the song, there is a sense of longing for a better life and a hopeful determination to overcome the challenges faced. It reflects the struggles and experiences of many people growing up in marginalized communities and their aspirations for a brighter future. Overall, "Departure" is a heartfelt and poignant exploration of personal struggles, loss, and the pursuit of one's dreams, all set against the backdrop of a harsh and unforgiving environment.