The song "Heroin" by Lou Reed, John Cale, and Nico explores the theme of drug addiction, particularly heroin, and the destructive nature it can have on an individual's life. The lyrics depict a person who is lost and unsure of their direction in life, seeking solace and escape through the use of drugs. The song begins with the narrator acknowledging their uncertainty about where they are going but expressing a desire to try for something greater, even if it means resorting to drug use. They describe the fleeting sense of empowerment and spiritual connection they feel when under the influence, comparing themselves to Jesus' son. As the song progresses, the narrator makes the decision to "nullify" their life through heroin, seeing it as an escape from the struggles and pressures of society. They reject the support and companionship of others, dismissing their pleas for help and interaction. The addictive nature of the drug is portrayed when the narrator mentions the blood flowing through the dropper's neck, implying the act of injecting heroin. The lyrics also touch on a longing for the past and a simpler, less corrupted time. The narrator yearns to sail the seas and escape the confines of the city, free from the evils both around them and within themselves. They express a sense of despair and disillusionment, highlighting the societal and political issues present in their world. The repetitive refrain of "I guess that I just don't know" signifies the narrator's confusion, uncertainty, and resignation towards their addiction. They seem to be caught in a cycle of dependency and apathy, where the drug has become their focus, numbing them both physically and emotionally. Ultimately, the song presents a dark and bleak perspective on addiction, highlighting the destructive power of heroin and the toll it takes on the user's life. It serves as a cautionary tale and an exploration of the depths of despair and detachment that can accompany drug dependency.