E-40's song "Gamed Up" is about his experience and knowledge gained from growing up in the streets and the music industry. The lyrics reflect his confidence, resilience, and ability to see through deception. In the hook, Rayven Justice sings about E-40's experience, stating that he is not new to the streets and can't be easily fooled or manipulated. He has been in the game for a long time and has learned the ins and outs, making him "gamed up." In the verses, E-40 talks about his upbringing and how he learned from older peers who have experienced both success and failures in street life and the music industry. He emphasizes his ability to navigate through challenges and remain determined to achieve his dreams, comparing himself to a king and a hustler. E-40 also mentions his habits of drinking, smoking, and staying cautious due to the dangers of the streets. He warns others not to expect his help if they can't help themselves and highlights his knowledge of the streets and its intricacies, comparing it to the expertise of the Gracies in Jiu-Jitsu. The song also touches on E-40's success and how he has transitioned from a struggling artist to a respected figure in the industry. He refers to his rise in status, acquiring money, and gaining attention or notoriety. He mentions his past struggles and how he used to have fewer resources but has now achieved a more luxurious lifestyle. Throughout the song, E-40 emphasizes his wisdom, experiences, and ability to stay ahead in the game. He warns against jealousy and advises listeners to learn from successful people rather than hate on them. He also mentions the dangers of his hometown in the Wild West and the need to be cautious when visiting. Overall, "Gamed Up" showcases E-40's street smarts and his journey from the streets to becoming a respected and successful artist in the music industry.