The song "Go" by E-40 reflects on the importance of family and financial success, while also highlighting the challenges and betrayals in life. The lyrics suggest that all E-40 needs in life are his family and financial dividends. He emphasizes that he doesn't need any new friends because he has realized that people he thought were trustworthy turned out to be unreliable, comparing them to "salad" - untrustworthy or fake. E-40 mentions being tipsy and smoking marijuana, as well as sipping on Kuiper Belt, which is a reference to E-40's own brand of bourbon. This conveys his carefree attitude and enjoyment of indulgences. He acknowledges that he may not be entirely mentally present, stating that everyone knows he is not "all the way there." This suggests that he may occasionally make impulsive or irrational decisions. E-40 also emphasizes his confidence and desire to speak his mind, regardless of others' opinions. He enjoys the attention and is unapologetic about dominating conversations. He mentions drinking heavily and having a triple shot in his cup, indicating his readiness to confront and fight if necessary. The lyrics continue to touch on altercations, where E-40 implies that anyone can be a target if they provoke him or disrespect him. He implies that confrontations can be resolved with just a small amount of money, referring to it as "chump change." E-40 describes the late-night hours as being notorious for violence, stating that things can turn sour and dangerous at 4 a.m., often referred to as "the murder hours." The chorus, "Go, run," can be interpreted as a warning to those who may encounter E-40 and his unpredictable nature. It suggests that they should flee or avoid engaging with him to prevent any confrontations or altercations. In the second verse, E-40 references his willingness to face the consequences of his actions and never confess to any wrongdoings. He compares himself to a character from the TV series Game of Thrones known for his love of alcohol. E-40 also mentions gambling for push-ups when playing a bone-slapping game, indicating his affinity for taking risks and maintaining a competitive spirit. He mentions having expensive jewelry with certified diamonds, which might attract attention from potential thieves. E-40 advises being cautious about what is said on the phone, as someone might be listening. He further emphasizes the importance of maintaining a polished appearance and owning a firearm for self-defense. E-40 acknowledges that criminal activities, such as theft, church burnings, and vandalism, are present in his surroundings. He suggests that these actions are part of the environment and cannot be avoided, referring to them as "sucker shit." The lyrics also touch on E-40's enjoyment of good food and wealth, referencing "chalupa" and "gouda." He concludes the song by stating that if someone is not looking for trouble, they should not engage with him. Overall, "Go" reflects E-40's confidence, resilience, and readiness to protect what is his while cautioning others to be mindful of their actions and surroundings.