"Smoke 'N Drank" by E-40 is a song that revolves around the themes of partying, alcohol, and drug use. The lyrics describe the experiences of the narrator, who reminisces about their early years engaging in various indulgences such as drinking, experimenting with moonshine and different types of wines. The narrator mentions standing in front of a liquor house to obtain their desired drinks from older individuals. It is evident that they have a penchant for alcohol and possibly other substances. The chorus emphasizes the desire to continue indulging in these activities, including smoking and drinking, with the intention of getting high and loaded once again. The repetition of the chorus emphasizes the narrator's eagerness to continue their drug-fueled lifestyle. The verse describes a morning after a night of heavy consumption, during which the narrator wakes up with a hangover but still feels high. They express a desire to never be sober and compare the feeling of being intoxicated to being "toishin" (slang for intoxicated). The lyrics suggest that the narrator is fond of the sense of escape and altered reality that intoxication provides. The song also references specific characters and situations, such as an old television commercial featuring Jackie Stallone and encounters with law enforcement. These references add a sense of nostalgia and specificity to the narrator's experiences. Overall, "Smoke 'N Drank" portrays a narrative centered around partying, excess, and the desire to maintain a continuous state of intoxication through the consumption of drugs and alcohol.