"Pharmaceuticals" is a song by Esham, an American rapper from Detroit. The lyrics of the song are explicit and contain vulgar language. The song discusses various themes including violence, sexual encounters, drug use, and Esham's disdain for other rappers. The lyrics open with Esham asserting his confidence and disregarding any apologies. He references oral sex and boasts about his sexual conquests. He also criticizes Twitter and dismisses any requests for attention or validation, using the hashtag "nigga please." Esham continues by describing his dominance and control over women, using derogatory language. He contrasts his pursuit of money with others' desire for casual sex. He proclaims that he will take what he wants from others, implying that he will use force or manipulation to obtain it. The lyrics then mention Esham's detachment from emotions and his desire for death. He expresses a desire to cry and suggests that other rappers should commit suicide. This could be interpreted as Esham's frustration with the rap industry and his belief that many artists lack genuine talent. Esham uses violent imagery to convey his disregard for other rappers' skills. He refers to himself as a threat, comparing his rivals to fish that will be disposed of and taking a "long ride." He claims to represent the streets while mocking someone who supports gay rights. Esham continues with provocative language, discussing his sexual encounters and money. He boasts about his self-perceived superiority and suggests that others depend on him for guidance. He compares his mindset to being the best, while implying that others think of themselves as nothing more than feces. Mocking other rappers, Esham claims to have ended their careers and insults the rap industry, referring to it as full of cowardly individuals (pussies) in need of medical attention (pap smear). He specifically mentions Detroit as a dangerous place and implies that violence is prevalent there. Esham expresses his disdain for law enforcement and implies that he carries a firearm. He suggests that his lack of a Rolex watch signifies his defiance of societal norms. He criticizes radio stations and their portrayal of him as a vigilante, while highlighting that fans continue to adore him. In the final verse, Esham challenges other rappers to a battle, asserting his dominance and claiming responsibility for their downfall. He suggests that he is laughing at their misfortunes and does not have any advice or sympathy for young artists. The song ends with a sinister tone, indicating Esham's satisfaction in the demise of his rivals. Overall, "Pharmaceuticals" is a controversial and provocative song that showcases Esham's aggressive and confrontational style. The lyrics touch on themes of violence, sexual encounters, materialism, and Esham's perceived superiority in the rap industry.